As Jessie, James, and Meowth are plotting yet again to steal Pikachu, they are interrupted by two mysterious figures: a hooded woman known only as Madame X, and Malamar, a Pokémon with incredible hypnotic powers. Jessie and James quickly fall under its spell, but Meowth manages to escape—and runs right into our heroes!

Ash, Serena, Clemont, and Bonnie help get the injured Meowth back on his feet, and he warns them that Madame X and Malamar are coming for Pikachu. They soon show up along with the mind-controlled Jessie and James, swoop Pikachu up with Malamar’s Psychic, and take off toward their hideout.

Clemont has a new invention, a Pikachu-shaped robot designed to track down Pikachu’s energy signature, and they follow it to an observatory...where it gets stuck in the fence and explodes. Clemont makes some quick repairs, and then Bonnie spots Officer Jenny’s motorcycle parked outside the building. When our heroes investigate, they find Madame X inside—along with Pikachu, who’s fallen under Malamar’s spell! Malamar quickly puts Serena, Bonnie, and Clemont under hypnosis as well, but Meowth attacks Ash to keep him focused.

Pikachu initially obeys Madame X’s order to stop Ash at all costs, but the bond between Ash and Pikachu is stronger than any hypnotic power, and Pikachu manages to shake off the trance. Then the Pikabot, which has resumed its tracking, bursts onto the scene. It slams into Malamar, disrupting its powers, and everyone is returned to normal—including Madame X, who throws off her hood to reveal that she’s really Officer Jenny!

Malamar does some gloating, and Meowth translates. Apparently Malamar had a master plan to use a mind-control device to take over the world. Controlling Officer Jenny to turn her into its accomplice was only the first step, but now that its plan has been discovered, it’s decided to destroy the device. Everyone runs for it as the entire building explodes, but Malamar escapes! What will become of its master plan?